Dose calculation accuracy of clinical radiotherapy plans using next generation cone beam computed tomography imaging technology.

ABSTRACT:

Background and purpose

Next generation cone beam computed tomography (CBCT) technology has shown improved Hounsfield unit accuracy over standard CBCT, and comparable to that of fan beam CT simulators (CTsim), potentially allowing direct dose calculation on CBCT. In this study, we evaluated the dose calculation accuracy of clinical treatment plans calculated using this technology, compared with standard CBCT.

Materials and methods

Thirty subjects with thoracic or upper abdominal cancer were imaged on CTsim, standard CBCT and next generation CBCT, and treated using breath hold techniques. Both CBCT image sets were rigidly registered to CTsim, and clinical treatment plans were forward calculated on all images. 3D Gamma analysis was used to evaluate CBCT dose distributions relat

SUBMITTER: Martin PR 

PROVIDER: S-EPMC11985121 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature