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Prediction of the prognosis of intrahepatic cholangiocarcinoma patients after hepatectomy via propensity score matching: a competitive risk model analysis.


ABSTRACT:

Background

Hepatectomy represents the cornerstone therapeutic approach for intrahepatic cholangiocarcinoma (ICCA); however, research pertaining to the prognosis of ICCA patients utilizing competing risk models remains scarce. This study aimed to construct a prognostic model utilizing competing risk analysis to predict cancer-specific survival (CSS) among ICCA patients posthepatectomy.

Methods

This study retrospectively analyzed ICCA patients from the Surveillance, Epidemiology, and End Results (SEER) database (2004-2015) who underwent hepatectomy. Patients were randomly allocated to the training (70%) and validation (30%) cohorts, with baselines balanced via propensity score matching (PSM). Prognostic factors were ascertained through both univariate and multivariate analyses

SUBMITTER: Jiang SS 

PROVIDER: S-EPMC11985192 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature