Necessity of induction agent modification for old age kidney transplant recipients.

ABSTRACT:

Background

Immunosenescence gradually deteriorates the function of the immune system, making elderly patients susceptible to infection, while reducing rejection of organ transplants. Therefore, age-adaptive immunosuppression is necessary in the elderly. We evaluated clinical outcomes such as rejection and infection rate when using basiliximab and rabbit anti-thymocyte globulin (r-ATG) as induction agents in elderly and young organ transplant recipients.

Methods

We retrospectively reviewed patients who underwent kidney transplantation (KT) between June 2011 and April 2019. We enrolled 704 adult KT patients and classified the patients into groups according to patient age. We compared the outcomes of infection and biopsy-proven acute rejection (BPAR) according to the type of in

SUBMITTER: Kim KD 

PROVIDER: S-EPMC11985316 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature