Utilization of potentially inappropriate sedative-hypnotic and atypical antipsychotic medications among elderly individuals with insomnia and Alzheimer's disease.

ABSTRACT:

Study objectives

This study assessed the utilization of potentially inappropriate medications (PIM) including oral sedative-hypnotic and atypical antipsychotic (OSHAA), healthcare resource utilization (HCRU), and costs among elderly individuals with insomnia and in the subpopulation with Alzheimer's disease (AD) who also had a diagnosis of insomnia.

Methods

Using a claims database containing International Classification of Diseases, 10th Revision (ICD-10) codes, the cohort included individuals aged ≥ 65 with incident insomnia (EI, N = 152 969) and AD insomnia subpopulation (ADI, N = 4888). The proportion of patients utilizing atypical antipsychotics or oral sedative-hypnotic medications, namely z-drugs, benzodiazepines, doxepin, dual orexin receptor antagonists (DORAs), and

SUBMITTER: Chekani F 

PROVIDER: S-EPMC11985390 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature