Visualizing the genome: techniques for presenting human genome data and annotations.

ABSTRACT:

Background

In order to take full advantage of the newly available public human genome sequence data and associated annotations, biologists require visualization tools ("genome browsers") that can accommodate the high frequency of alternative splicing in human genes and other complexities.

Results

In this article, we describe visualization techniques for presenting human genomic sequence data and annotations in an interactive, graphical format. These techniques include: one-dimensional, semantic zooming to show sequence data alongside gene structures; color-coding exons to indicate frame of translation; adjustable, moveable tiers to permit easier inspection of a genomic scene; and display of protein annotations alongside gene structures to show how alternative splicing impact

SUBMITTER: Loraine AE 

PROVIDER: S-EPMC119855 | biostudies-literature | 2002 Jul

REPOSITORIES: biostudies-literature