Ultrafast synthesis of L-His-Fe₃O₄ nanozymes with enhanced peroxidase-like activity for effective antibacterial applications.

ABSTRACT: Background: Bacterial resistance remains a significant challenge, necessitating the development of new antibacterial strategies. This study introduces a rapidly synthesized L-histidine- Fe₃O₄ (L-His-Fe₃O₄) nanozyme with enhanced peroxidase (POD)-like activity, designed to improve antibacterial efficacy and accelerate the healing of bacteria-infected wounds. Methods: We successfully synthesized L-His-Fe₃O₄ using an ultrafast, room-temperature synthesis method, and observed its anti-infection effect and explored its anti-infection mechanism through in vivo and in vitro antibacterial experiments. Results: We produced L-His-Fe₃O₄ cost-effectively while preserving L-His, wh

SUBMITTER: Yuan Y 

PROVIDER: S-EPMC11985857 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature