Influence of SSRI and SNRI co-prescription on benzodiazepine prescription trajectories.

ABSTRACT:

Purpose

This study examined whether co-prescription of selective serotonin reuptake inhibitors (SSRIs) or serotonin or norepinephrine reuptake inhibitors (SNRI)s with benzodiazepines is associated with differences in benzodiazepine prescriptions both within individual patients over time and between patients.

Methods

We analyzed deidentified electronic health records of patients prescribed a benzodiazepine between 2020 and 2022 (N = 847). Patients were categorized into three groups: those co-prescribed an SSRI, those co-prescribed an SNRI, and those not co-prescribed an SSRI or SNRI.

Results

Individuals co-prescribed an SSRI (M=6.63) or an SNRI (M=8.31) had more benzodiazepine prescription encounters than those who were not co-prescribed an SSRI/SN

SUBMITTER: Kinney KL 

PROVIDER: S-EPMC11986241 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature