Blood eosinophil reference values and determinants in a representative adult population.

ABSTRACT:

Background

The use of blood eosinophil count (BEC) as a prognostic biomarker in the management of conditions such as asthma and chronic obstructive pulmonary disease (COPD) may be complicated by factors such as atopy, age, sex, smoking, and comorbidities.

Objective

We sought to produce reference values for BEC, considering age, asthma, COPD, and clinical allergy for the general adult population.

Methods

The West Sweden Asthma Study constitutes a population-representative clinical epidemiological cohort of randomly selected adults in Western Sweden. From this cohort, 1145 individuals took part in clinical examinations, including skin prick testing, specific IgE, and BEC.

Results

The upper limit (95th percentile) of BEC varied by age. It ranged from 400 to 500 ce

SUBMITTER: Abohalaka R 

PROVIDER: S-EPMC11986508 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature