Evaluation of different methods for antibody titre determination in ABO-incompatible kidney transplantation.

ABSTRACT:

Background

Blood type antibody-mediated rejection is considered the main obstacle to ABO blood type-incompatible kidney transplantation. Choosing an appropriate antibody-level determining method and setting a rational baseline are critical for safely conducting ABO-incompatible kidney allografts. However, due to the differences in antibody detection methods between laboratories, there is no unified baseline to confirm the true titer. Therefore, a generally applicable method must be selected to determine the level of anti-ABO antibodies before surgery, and the actual critical titer level should be set accordingly. This study aims to guide the selection of appropriate antibody titer detection methods for ABO-incompatible kidney transplant recipients by comparing the differences in ti

SUBMITTER: Zhou S 

PROVIDER: S-EPMC11986527 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature