Effect of respiratory phase on three-dimensional quantitative parameters of pulmonary subsolid nodules in low-dose computed tomography screening for lung cancer.

ABSTRACT:

Background

In the screening of pulmonary subsolid nodules (SSNs), it is crucial to compare the quantitative parameters under consistent computed tomography (CT) acquisition conditions, including the same degree of lung inflation. When non-end-inspiratory chest CT scan is performed due to poor breath holding, there is a risk of inaccurate measurement of quantitative parameters and erroneous assessment of pulmonary nodule growth. This study aims to investigate the effect of respiratory phase on three-dimensional (3D) quantitative parameters of SSNs, and to further explore the impact of respiratory phase change on the judgment of SSNs growth during the follow-up of low-dose CT (LDCT) screening.

Methods

There were 255 pulmonary SSNs retrospectively found in 230 subjects who rece

SUBMITTER: Zhang H 

PROVIDER: S-EPMC11986747 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature