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Anticancer and Antioxidant Activities of Rhizospheric Soil Bacteria of <i>Lophocereus marginatus</i>.


ABSTRACT: Identification of new sources of compounds with anticancer and antioxidant potential is essential for cancer treatment. Rhizospheric bacteria have emerged as a promising source of these agents. This study is aimed at investigating the anticancer and antioxidant properties of bacteria isolated from the rhizosphere of Lophocereus marginatus. Six rhizobacteria of L. marginatus were isolated and molecularly identified by sequencing the 16S rRNA gene and MALDI-TOF. We evaluated the inhibitory activity of methanol (MeOH) and ethyl acetate (EtOAc) extracts obtained from rhizobacteria against the murine lymphoma cell line L5178Y-R, as well as normal Vero monkey kidney cells and peripheral blood mononuclear cells (PBMCs). Compared with those of normal cells, the MeOH extract of Pae

SUBMITTER: Ramirez-Villalobos JM 

PROVIDER: S-EPMC11987078 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature