Investigating the antimicrobial activity of 1-heteroaryl benzotriazole silver compounds.

ABSTRACT: Five (1-5) Ag(i) compounds, derived from different N,N'-bidentate 1-heteroaryl benzotriazole ligands, were synthesised and characterised using SXRD, IR, UV-Vis, elemental analysis, ESI-MS, and NMR. Variations in ligands and counter-anions produced distinct structures and morphologies. Preliminary antimicrobial testing at the micromolar level, in DMSO, revealed that only compound 2, based on 1-(2-pyridyl)benzotriazole and triflate anion, exhibited interesting antimicrobial properties, thus marking the introduction of a new class of Ag(i) compounds in medicinal inorganic chemistry.

SUBMITTER: Elzein A 

PROVIDER: S-EPMC11987083 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature