Phase-Amplitude Coupling of NREM Sleep Oscillations Shows Between-Night Stability and is Related to Overnight Memory Gains.

ABSTRACT: There is growing evidence in humans linking the temporal coupling between spindles and slow oscillations during NREM sleep with the overnight stabilization of memories encoded from daytime experiences in humans. However, whether the type and strength of learning influence that relationship is still unknown. Here we tested whether the amount or type of verbal word-pair learning prior to sleep affects subsequent phase-amplitude coupling (PAC) between spindles and slow oscillations (SO). We measured the strength and preferred timing of such coupling in the EEG of 41 healthy human participants over a post-learning and control night to compare intra-individual changes with inter-individual differences. We leveraged learning paradigms of varying word-pair (WP) load: 40 WP learned to a minimum cr

SUBMITTER: Cross N 

PROVIDER: S-EPMC11987483 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature