Genomic surveillance and evolutionary dynamics of respiratory syncytial virus circulating in Tunisia post-COVID-19 pandemic lockdown restrictions.

ABSTRACT:

Objectives

Human respiratory syncytial virus (hRSV) is the leading cause of severe respiratory infections in children worldwide. Severe cases often require intensive care. Respiratory syncytial virus (RSV) is classified into two main antigenic groups: RSV-A and RSV-B. Recent molecular advancements have significantly enhanced our ability to control and understand RSV infections. This study investigated the epidemiologic and genetic characteristics of the RSV in Tunisia, focusing on its evolutionary dynamics.

Methods

Between October and December 2021, 92 samples were collected from Tunisian patients hospitalized for mild-to-severe acute respiratory infections. Laboratory analyses, including real-time reverse transcription-polymerase chain reaction and whole genome sequencing (

SUBMITTER: Romano G 

PROVIDER: S-EPMC11987636 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature