Treatment patterns and outcomes in advanced or metastatic gastric/gastroesophageal junction adenocarcinoma in China.

ABSTRACT:

Aims

Describe the characteristics, treatment patterns and outcomes of Chinese patients with unresectable advanced/metastatic (UAM) gastric/gastroesophageal junction adenocarcinoma (GA/GEJA).

Methods

This multicenter, retrospective, observational study included adults diagnosed with UAM GA/GEJA in China from 2017-2020.

Results

Among 2,745 patients, 1,902, 729, and 284 received first-, second- and third-line (1 L, 2 L and 3 L) therapy-respectively. Most patients received chemotherapy alone in 1 L (84.1%) and 2 L (63.6%), and targeted-therapy-based treatment in 3 L (49.2%). Median real-world progression-free survival (rwPFS) was 6.5, 4.2, and 3.2 months in 1 L, 2 L, and 3 L, respectively.

Conclusions

Chinese patients with UAM GA/GEJA mainly received chemotherapy a

SUBMITTER: Zhang J 

PROVIDER: S-EPMC11988209 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature