Outcomes of Salvage Treatment After Primary Treatment for Renal Cell Cancer: A Systematic Review.

ABSTRACT: Background/Objective: The grade of recommendation for renal cell carcinoma (RCC) salvage treatment options is weak. The aim of the current study is to summarize available evidence about the surgical, oncological, and functional outcomes of salvage renal options after previous treatments for RCC. Methods: A systematic search (PROSPERO: CRD42024618629) was performed according to the PRISMA statement. A pooled analysis was performed to quantify the effect size (ES) for an overall postoperative Clavien-Dindo (CD) grade ≥ III and postoperative and intraoperative complications for either partial or radical nephrectomy (PN or RN) subgroups. Results: Overall, 11 studies involving 331 patients were included in the final analysis. The median age ranged from 44 to 75 years. Prima

SUBMITTER: Longo N 

PROVIDER: S-EPMC11988335 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature