Integrated Transcriptome and Metabolome Analyses Reveal Candidate Genes Associate with Phenolic Compound Biosynthesis in Different Varieties of <i>Perilla frutescens</i>.

ABSTRACT: Perilla frutescens (Perilla) has great potential for utilization in food and medicine due to the abundance of secondary metabolites, especially phenolic compounds. However, the molecular mechanism underlying phenolic compound synthesis in perilla remains poorly understood. By targeted metabolome analysis, we found nine differentially accumulated metabolites among QS2, QS6, and QO7 leaves and nine unique metabolites which only exist in QS6. Furthermore, transcriptome analysis showed the differential expression genes (DEGs) were significantly enriched into phenylpropanoid- and flavonoid-related pathways. Moreover, the integrated transcriptome and metabolome analyses indicated 14 candidates highly correlated with phenolic compound biosynthesis. In addition, phenylpropanoid- and flavono

SUBMITTER: Ye H 

PROVIDER: S-EPMC11988548 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature