Integrative Utilization of Transcriptomics and Metabolomics Sheds Light on Disparate Growth Performance of Whiteleg Shrimp, <i>Litopenaeus vannamei</i>.

ABSTRACT: Litopenaeus vannamei is a key economic species in aquaculture, yet the molecular mechanisms underlying its growth variability remain unclear. This study conducted transcriptomic and metabolomic analyses of fast-growing (NL) and slow-growing (NS) shrimp under identical conditions. A total of 1280 differentially expressed genes (DEGs) related to protein processing, ribosomes, and oxidative phosphorylation, along with 5297 differentially abundant metabolites (DMs) involved in arginine biosynthesis, amino acid metabolism, and pantothenate and CoA biosynthesis, were identified and analyzed. An integrative analysis revealed that the NL shrimp exhibited an enhanced retinol, glutathione, riboflavin, and purine metabolism, which implies a higher tolerance to environmental stress. In contrast

SUBMITTER: Zhang X 

PROVIDER: S-EPMC11988672 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature