Axis I Psychiatric Disorders and Substance Abuse: A Systematic Review of Neuroimaging Findings.

ABSTRACT: Background/Objectives: The present systematic review analyses the neuroradiological findings in subjects with axis I psychiatric disorders (i.e., bipolar, major depressive, schizophrenic, anxiety, and post-traumatic stress disorders) and comorbid substance use disorder in order to elucidate the organic changes that occur in the brains of people suffering from both conditions. Methods: We analysed and compared the different neuroimaging findings extracted from 93 studies and 10,823 patients; articles were obtained from three databases (Scopus, PubMed [Medline], and the Cochrane Controlled Register of Trials [Central]) and subjected to specific eligibility criteria. We selected articles that assessed patients with axis I psychiatric conditions and a comorbid substance abuse dis

SUBMITTER: Sosa-Moscoso B 

PROVIDER: S-EPMC11989531 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature