Chemical Profile Analysis of <i>Prosopis laevigata</i> Extracts and Their Topical Anti-Inflammatory and Antibacterial Activities.

ABSTRACT: There are two major global morbidity and mortality problems in the health sector: inflammation, which is the physiological process that, in acute and chronic conditions, gradually causes the loss of the body's functionality, leading to severe damage to health; and microbial diseases, which are caused by pathogenic microorganisms such as bacteria. In the present study, the anti-inflammatory effects of three extracts of mesquite (Prosopis laevigata)-n-hexane (PH), dichloromethane (PD), and methanol (PM)-were assessed in a mouse model of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, and the antimicrobial effects against 14 microorganisms were assessed using the broth microdilution method. The extracts inhibited ear oedema by 60.81% (PH), 75.96% (PD), and

SUBMITTER: Gonzalez-Cortazar M 

PROVIDER: S-EPMC11991005 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature