Magnetic Resonance Elastography Combined With PI-RADS v2.1 for the Identification of Clinically Significant Prostate Cancer.

ABSTRACT:

Background

Multiparametric MRI may cause overdiagnosis of clinically significant prostate cancer (csPCa) with the Prostate Imaging Reporting and Data System version 2.1 (PI-RADS v2.1).

Objectives

To investigate the diagnostic performance of stiffness as a standalone and complementary marker to PI-RADS v2.1 for diagnosing csPCa.

Study type

Prospective.

Subjects

One hundred forty-seven participants with pathologically confirmed prostate lesions (≥1 cm), including 71 with csPCa.

Field strength/sequence

T1-weighted fast spin-echo, T2-weighted fast spin-echo, single-shot echo-planar diffusion-weighted imaging, fast 3D gradient-echo T1-weighted dynamic contrast-enhanced imaging, and 3D single-shot spin-echo based echo-planar MR elastography at 3.0 T.

Assess

SUBMITTER: Chen J 

PROVIDER: S-EPMC11991885 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature