Enhanced metabolic regulation in II/R injury: Comparing multiroute and monoroute enteral nutrition.

ABSTRACT:

Objective

This study aimed to compare the effects of enteral nutrition (EN) administered via multiroute or via monoroute on metabolic regulation in intestinal ischemia-reperfusion (II/R) injury rat model.

Methods

The rats were divided into sham operation and II/R injury groups. The rats in each group were further treated with either multiroute or monoroute EN. Rats subjected to multiroute EN were administered a continuous infusion of 30 kcal/kg × day of nutrition via a gastric tube and additionally provided with 0.5 g of standard rat forage for oral intake q8h (for a total of approximately 20 kcal/kg × day) each day. Conversely, rats on the monoroute regimen underwent a continuous infusion of 50 kcal/kg × day of EN through a gastric tube. Hypercatabolism was evaluated by ass

SUBMITTER: Duan J 

PROVIDER: S-EPMC11992551 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature