Individualized prediction of stent patency in malignant colonic obstruction: development and validation of a prognostic model.

ABSTRACT:

Purpose

To develop and validate a predictive model for stent patency following a palliative self-expandable metallic stent (SEMS) for primary malignant colonic obstruction.

Methods

Patients with primary malignant colonic obstruction who underwent SEMS treatment were included in this study. One retrospective set (N = 121) was used to develop and validate the predictive model. The clinical features were collected and subjected to Cox regression analyses. The final predictive model was displayed as a nomogram, which was validated in an independent set (N = 36).

Results

The clinical prognostic model was composed of pre-chemotherapy (P < 0.001), time of obstruction (P = 0.005), and post-chemotherapy (P < 0.001). The time-dependent area under the curve were 0.898 at 30-day,

SUBMITTER: Wan Y 

PROVIDER: S-EPMC11992713 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature