Gastrointestinal cytomegalovirus infection in persons with HIV: a retrospective case series study.

ABSTRACT:

Background

Gastrointestinal (GI) cytomegalovirus (CMV) infection remains an important cause of morbidity among persons with HIV (PWH), even in the late antiretroviral therapy (ART) era. However, its varied clinical presentations and outcomes are not fully understood.

Methods

We conducted a retrospective review of 21 PWH with histologically confirmed GI-CMV infections admitted to a tertiary hospital in Nanjing, China, between September 2018 and September 2023. Clinical features, endoscopic findings, histology, treatment responses, and outcomes were examined.

Results

Patients were predominantly male (95.2%) with a median age of 42 years. Over 80% had CD4 cell counts below 50 cells/µL; at admission, they were not on effective ART or had only recently initiated it, with a

SUBMITTER: Fang M 

PROVIDER: S-EPMC11992835 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature