Ultrasound-based versus immediate biopsy-based management of postmenopausal bleeding in non-Hispanic Black and non-Hispanic White individuals.

ABSTRACT:

Background

Ultrasound-based evaluation of endometrial thickness to rule out endometrial cancer in patients with postmenopausal bleeding (PMB) is not sufficiently validated in the non-Hispanic Black (NHB) population. Differences in ultrasound performance between NHB and non-Hispanic White (NHW) patients may contribute to documented disparities in cancer-associated survival.

Methods

We developed a decision-tree model, informed by literature and institutional data, comparing an immediate biopsy-based strategy (BBS) to an ultrasound-based strategy (UBS) to evaluate PMB in NHB and NHW patients. Primary outcomes were the probability of a missed cancer diagnosis and incremental biopsies per additional cancer detected. Fibroid prevalence, endometrial visibility, and race were modele

SUBMITTER: Nolin AC 

PROVIDER: S-EPMC11993335 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature