Novel vs established cryoballoon ablation system for atrial fibrillation: A systematic review and meta-analysis.

ABSTRACT:

Background

Recently, a novel cryoballoon ablation system (POLARx) for the treatment of atrial fibrillation has been introduced.

Objective

We aimed at systematically reviewing the efficacy and safety of the POLARx compared with the ArcticFront system.

Methods

Structured systematic database search for articles published between 2021 and 2024 reporting the efficacy and/or safety of the POLARx system for atrial fibrillation ablation. The co-primary endpoints were the long-term efficacy and safety of the POLARx system.

Results

Of the 24 studies with 5364 patients (weighted mean age 62.4 years) included, 15 compared the POLARx system (1746 patients) with the ArcticFront system (2282 patients). Despite significantly lower temperatures at isolation (POLARx -46.3 °C, Ar

SUBMITTER: du Fay de Lavallaz J 

PROVIDER: S-EPMC11993791 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature