Long-term weight change patterns in American adulthood in relation to gallstones: evidence from NHANES.

ABSTRACT:

Background

The aim of this study is to investigate the association between weight change patterns across adulthood and gallstones in the United States.

Methods

The analysis is based on data from participants aged 40-70 years taken from the National Health and Nutrition Examination Survey 2017-2020. Weight status and weight change patterns were categorized based on body mass index at three time points. Weighted logistic regression was used to estimate the association of weight status at the three time points and weight change patterns over the three periods with gallstones.

Result

Compared with normal weight, obese status at age 25 was associated with an 86% increased risk of gallstones (OR 1.86, 95%CI 1.07-3.24). No significant associations were observed for underweig

SUBMITTER: Chen P 

PROVIDER: S-EPMC11993937 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature