Clarithromycin-resistant Helicobacter pylori in Africa: a systematic review and meta-analysis.

ABSTRACT:

Background

In 2022, approximately 56.5% of adults and 47.1% of children and adolescents were affected by Helicobacter pylori (H. pylori) infection in Africa, and clarithromycin-resistant H. pylori (CRHp) strains have become global priority pathogens. Therefore, this study aimed to conduct the first comprehensive systematic review and meta-analysis of CRHp in Africa.

Methods

This investigation was conducted according to the guidelines of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (The PRISMA 2020). Literature search of electronic databases (Google Scholar, African Journals Online, ResearchGate, PubMed, Embase, and Scopus) was performed using keywords "clarithromycin", "Helicobacter pylori", "African country name", "mutation in the 23S rRNA".

Res

SUBMITTER: Dossouvi KM 

PROVIDER: S-EPMC11993951 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature