Enhancing prediction of cervical lymph node metastasis in papillary thyroid carcinoma through nodule-oriented quantification: combined S-Detect and ultrasound elastography.

ABSTRACT:

Background

Papillary thyroid carcinoma (PTC) frequently metastasizes to cervical lymph nodes (LNs), with metastasis rates of 20-90%, significantly impacting patient prognosis. Although ultrasound (US) is the primary preoperative assessment tool, its accuracy (Acc) in detecting LN metastasis (LNM) remains insufficient, with conventional US detecting only 50% of confirmed cases. This study aimed to improve the prediction of cervical LNM in PTC by combining quantitative nodule orientation parameters with multi-modal US techniques.

Methods

Data were retrospectively collected from 117 patients (141 nodules: 85 non-metastasis and 56 metastasis) who underwent PTC resection and cervical LN dissection from September 2023 to May 2024. All patients underwent US, US elastography (UE), a

SUBMITTER: Xu ZL 

PROVIDER: S-EPMC11994488 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature