Differentiation of inflammatory pseudotumors and malignant pulmonary nodules using the time-to-peak in first-pass dual-input volume computed tomography-perfusion.

ABSTRACT:

Background

Inflammatory pseudotumors (IPTs) are often misdiagnosed as malignant solitary pulmonary nodules (SPNs) because their imaging features overlap with those of malignant SPNs, leading to overtreatment. The purpose of this article was to investigate the value of first-pass enhanced time-to-peak (TTP) in distinguishing IPTs from malignant SPNs using dual-input volume computed tomography perfusion (DI-CTP).

Methods

This retrospective study included consecutive patients from No. 82 Group Hospital of Chinese People's Liberation Army with IPTs or malignant SPNs by surgery or biopsy from June 2016 to October 2021. Pulmonary artery flow (PF), bronchial artery flow (BF), perfusion index (PI), time-density curve, total perfusion (TLP), and first-pass TTP for all SPNs were deter

SUBMITTER: Guo C 

PROVIDER: S-EPMC11994533 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature