Quantitative magnetic resonance imaging in Alzheimer's disease: a narrative review.

ABSTRACT:

Background and objective

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline and is traditionally associated with grey matter pathology. Recent research highlights the significance of white matter and myelin damage in AD, presenting a paradigm shift in understanding the disease. The aim of this study was to summarize current advancements in magnetic resonance imaging (MRI) techniques and their applications in assessing myelin and brain pathology in AD with a special focus on ultrashort echo time (UTE) based techniques, alongside the role of artificial intelligence (AI) in enhancing diagnostic accuracy.

Methods

Between April and May 2024, we conducted a literature search using Google Scholar, Web of Science, and PubM

SUBMITTER: Malhi BS 

PROVIDER: S-EPMC11994541 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature