Quantification of infrapatellar fat pad fibrosis using magnetic resonance imaging-derived proton density fat fraction: a pathology-controlled study.

ABSTRACT:

Background

Knee osteoarthritis (KOA) is a degenerative joint disease leading to disability in the elderly. Fibrosis of the infrapatellar fat pad (IPFP) impacts knee joint function and disease progression. Accurate assessment of IPFP fibrosis aids early intervention and treatment. The aim of this study was to evaluate the diagnostic efficacy of proton density fat fraction (PDFF) and T2* measurements using mDixon-Quant technology in assessing IPFP fibrosis in KOA.

Methods

A total of 47 patients were included in this study (23 patients without fibrosis, 17 with mild fibrosis, and 7 with severe fibrosis). Knee magnetic resonance (MR) scans were performed on a 3.0 T MR system. MR sequences included 3.0 T, sagittal T2-weighted images, proton density-weighted spectral adiabatic inv

SUBMITTER: Zhou B 

PROVIDER: S-EPMC11994565 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature