Assessing pulmonary vascular remodeling in connective tissue disease-associated interstitial lung disease: a CT-based quantitative analysis.

ABSTRACT:

Background

It has recently become possible to quantitatively assess changes in the pulmonary arteries and veins on chest computed tomography (CT) images using automated software tools. The aim of this study was to assess the morphological characteristics of CT-based pulmonary arteries and veins to investigate pulmonary vascular remodeling in connective tissue disease-associated interstitial lung disease (CTD-ILD).

Methods

This retrospective study recruited 168 CTD-ILD patients (80 males; mean age, 62±10 years) who underwent standard of care pulmonary function testing (PFT) and CT evaluations. Gender-Age-Physiology (GAP) 1-3 staging was performed on the basis of gender, age, and PFT results. Arterial and venous analyses (volumes, densities, fractions, and tortuosity) were per

SUBMITTER: Li R 

PROVIDER: S-EPMC11994571 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature