Efficacy and safety of Tanshinone capsule in Acne vulgaris: a systematic review and meta-analysis.

ABSTRACT:

Objectives

To evaluate the efficacy and safety of Tanshinone capsule as a complementary therapy in managing of Acne Vulgaris.

Methods

A systematic search of six databases was conducted to identify relevant randomized controlled trials (RCTs) from each database for nearly 20 years (from 1 Jan 2004, to 1 June 2024). The Cochrane Handbook was used to evaluate the risk of bias. Meta-analysis was performed using Review Manager 5.4.1, and publication bias was assessed the Stata SE 12.0 software. GRADEpro was used to assess the quality of the evidence.

Results

A total of 2,969 participants from 28 studies were included. We found that Tanshinone capsules can reduce acne recurrence rates [risk ratio (RR) 0.44, 95% confidence interval (CI): 0.34 to 0.57, p < 0.000

SUBMITTER: Deng Y 

PROVIDER: S-EPMC11994734 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature