Embryo-Induced Changes in the Protein Profile of Bovine Oviductal Extracellular Vesicles.

ABSTRACT: The study of early maternal-embryonic cross-talk remains one of the most challenging topics in reproductive biology. Understanding the physiological mechanisms involved in the interactions between the maternal reproductive tract and the developing embryo is essential for enhancing bovine reproductive efficiency. This complex communication starts within the oviduct, where the modulation of biological processes important for ensuring embryo quality is partially facilitated through extracellular vesicles (EVs). Utilizing a combination of in vivo and in vitro models this study had three main objectives: 1) to examine the protein cargo of EVs isolated from the oviductal fluid (OF) of cyclic and pregnant heifers to understand their role in maternal-embryonic communication in vivo; 2) to characte

SUBMITTER: Mazzarella R 

PROVIDER: S-EPMC11994978 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature