Identifying studies evaluating susceptibility factors for chemical health assessments: A case study focused on methylmercury developmental neurotoxicity.

ABSTRACT: Identifying susceptibility factors for adverse health effects from chemical exposures is an important aspect of characterizing human health impacts. However, to date, an efficient approach for identifying these factors has not been established. To address this limitation, two approaches were utilized to find studies that contained susceptibility information using methylmercury (MeHg) developmental neurotoxicity (DNT) as a case study. Both approaches start with a comprehensive literature search of 5 databases on MeHg followed by keyword filtering for potential epidemiology studies; however, the approaches diverged for the subsequent steps. Approach 1 initially included screening of all 7,531 studies captured by the human filter, but was modified when it was determined that 96% of studies fo

SUBMITTER: Segal D 

PROVIDER: S-EPMC11995405 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature