Epidemiological characteristics and genomic analysis of respiratory adenovirus in Jining City from February 2023 to July 2024.

ABSTRACT:

Background

Human adenovirus (HAdV) infection can cause high fever, pneumonia, and even death, posing a serious threat to human health. This study analyzes the epidemiological characteristics and genetic features of respiratory adenovirus in Jining City from February 2023 to July 2024.

Methods

From February 2023 to July 2024, 3,947 throat swab specimens were collected from influenza-like illness cases at Jining First People's Hospital and Rencheng District Maternal and Child Health Hospital. Real-time fluorescent quantitative PCR was used to detect HAdV nucleic acid. Whole-genome sequencing was performed on HAdV-positive samples. Phylogenetic trees were constructed for the whole genome, Penton base gene, Hexon gene, and Fiber gene of HAdV, and protein variation sites were ana

SUBMITTER: Dou H 

PROVIDER: S-EPMC11995490 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature