A population-based cohort study of mitochondrial disease and mental health conditions in Ontario, Canada.

ABSTRACT:

Background

Mitochondrial disease has been linked to mental health disorder in clinical cohorts and post-mortem studies. However, a lack of population-level studies examining the relationship between mitochondrial disease and mental health has resulted in an evidence gap and creates a challenge for identifying and addressing care needs for the mitochondrial disease population. Using multiple linked population health databases in a single-payer health system that covers the full population, this study aimed to investigate the prevalence of mood disorders and other mental health conditions in patients with mitochondrial disease and to examine the joint impact of mitochondrial disease and mental health conditions on healthcare use and health system costs. To contextualize these finding

SUBMITTER: Rosella LC 

PROVIDER: S-EPMC11995528 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature