Pleiotropy increases parallel selection signatures during adaptation from standing genetic variation.

ABSTRACT: The phenomenon of parallel evolution, whereby similar genomic and phenotypic changes occur across replicated pairs of populations or species, is widely studied. Nevertheless, the determining factors of parallel evolution remain poorly understood. Theoretical studies have proposed that pleiotropy, the influence of a single gene on multiple traits, is an important factor. In order to gain a deeper insight into the role of pleiotropy for parallel evolution from standing genetic variation, we characterized the interplay between parallelism, polymorphism, and pleiotropy. The present study examined the parallel gene expression evolution in 10 replicated populations of Drosophila simulans, which were adapted from standing variation to the same new temperature regime. The data demonstrate t

SUBMITTER: Lai WY 

PROVIDER: S-EPMC11996171 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature