Extensive and diverse lanthanide-dependent metabolism in the ocean.

ABSTRACT: To date, the only known Lanthanide (Ln)-dependent enzymes are pyrroloquinoline quinone-dependent alcohol dehydrogenases. When compared to their Ca dependent counterparts, there is an emerging picture that Ln-dependent versions of these enzymes are generally more efficient, are preferentially upregulated in the presence of Ln when there is functional redundancy, and may even be evolutionarily older. Ln-utilising microbes have furthermore evolved diverse means of solubilizing and acquiring Ln, enabling them to utilize Ln even at trace concentrations. The ocean is the largest dissolved organic carbon pool on Earth, yet the diversity and prevalence of Ln-dependent carbon metabolisms in the ocean is unknown. Here we show that Ln-utilising methanol-, ethanol- and putative sorbose- and glucose-de

SUBMITTER: Voutsinos MY 

PROVIDER: S-EPMC11996626 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature