Clinical significance of NT-proBNP as a predictive biomarker of depressive symptoms in cardiac patients.

ABSTRACT:

Introduction

Depression is a significant comorbidity linked to poor subjective and objective health outcomes in cardiac patients. The paucity of data necessitates further research to elucidate the pathophysiological connection between depression and cardiac diseases in the presence of N-terminal pro-brain natriuretic peptide (NT-proBNP). Therefore, the current systematic review investigated the clinical significance of NT-proBNP as a predictive biomarker in cardiac patients with depressive symptoms.

Methods

Two researchers independently performed an extensive search of published literature from inception until April 2024 on PubMed, Web of Science, and Cochrane Library in accordance with the PRISMA guidelines. From a total of 452 records, 29 articles were eligible for full-te

SUBMITTER: Humayra S 

PROVIDER: S-EPMC11996918 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature