Macular inner retinal layers in multiple sclerosis.

ABSTRACT:

Aim

To evaluate the structural changes of individual inner retinal layers in the macular area and identify the most affected layer in subgroups of multiple sclerosis (MS) patients compared to healthy controls (HC).

Methods

In total, Optical coherence tomography (OCT) data from 507 MS patients and 183 HC were exported retrospectively. The MS patients were grouped according to MS sub-types, primary progressive (PP), Relapsing-Remitting (RR) and Secondary progressive (SP). Thickness of four inner retinal layers, the macula nerve fiber layer (NFL), ganglion cell layer (GCL), inner plexiform layer (IPL) and the inner nuclear layer (INL) were evaluated in nine sectors based on the Early Treatment Diabetic Retinopathy Study (ETDRS) map. The individual layer thickness measurements w

SUBMITTER: Zahavi O 

PROVIDER: S-EPMC11997350 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature