Nutraceutical supplement slim reshaped colon histomorphology and reduces <i>Mucispirillum schaedleri</i> in obese mice.

ABSTRACT:

Introduction

Bioactive compounds and whole foods have emerged as promising interventions to address gut microbiota dysbiosis linked to obesity. Compounds such as berberine and coenzyme Q10 are well-recognized for their roles in managing metabolic syndrome and exerting antioxidant effects, while beet pulp, rich in fiber and antioxidants, enhances gut health through additional prebiotic benefits.

Methods

This study evaluated the effects of a nutraceutical supplement, Slim, on the modulation of gut microbiota in obese mice induced by a high-fat diet.

Results

Our results demonstrated that Slim supplementation significantly improved lipid metabolism, reshaped colon histomorphology, and decreased levels of Mucispirillum schaedleri, which were correlated with VLDL-c a

SUBMITTER: Freitas JA 

PROVIDER: S-EPMC11997693 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature