Anterior prefrontal EEG theta activities indicate memory and executive functions in patients with epilepsy.

ABSTRACT:

Objective

Cognitive deficits are one of the most debilitating comorbidities in epilepsy and other neurodegenerative, neuropsychiatric, and neurodevelopmental brain disorders. Current diagnostic and therapeutic options are limited and lack objective measures of the underlying neural activities. In this study, electrophysiological biomarkers that reflect cognitive functions in clinically validated batteries were determined to aid diagnosis and treatment in specific brain regions.

Methods

We employed the Cambridge Neuropsychological Test Automated Battery (CANTAB) tasks to probe memory and executive functions in 86 patients with epilepsy undergoing clinical electroencephalography (EEG) monitoring. EEG electrode signals during performance of particular battery tasks were decompo

SUBMITTER: Hamedi N 

PROVIDER: S-EPMC11997909 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature