Stereotactic radiosurgery for vestibular schwannomas in neurofibromatosis type 2: a systematic review and meta-analysis.

ABSTRACT:

Background

Management of neurofibromatosis type 2 (NF2)- associated vestibular schwannomas (VSs) is challenging due to their multiplicity, early onset, proximity to the brainstem, unpredictable growth, and aggressive behavior. The optimal therapeutic intervention remains controversial in the literature, and the advantages and disadvantages of each treatment option should be evaluated for each patient. Stereotactic radiosurgery (SRS) has exhibited favorable results in the management of NF2-associated VSs. This systematic review and meta-analysis aimed to assess the role of SRS in NF2-associated VSs.

Methods

On August 22, 2024, four electronic databases, comprising PubMed, Embase, Scopus, and Web of Science, were comprehensively searched. Studies that assessed SRS's radiologic

SUBMITTER: Hajikarimloo B 

PROVIDER: S-EPMC11998438 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature