A novel model to predict age of respiratory syncytial virus infection from birth timing in relation to RSV circulation.

ABSTRACT: Respiratory syncytial virus (RSV) is a common respiratory virus that infects all children by age 2 to 3 years of age and causes the greatest morbidity at the extremes of life. Recent evidence suggests that early-life RSV infection, defined using active and passive surveillance with quantitative polymerase chain reaction- and serology-identified infection, is causal for childhood asthma. As such, identifying infants that are likely to be infected with RSV during this critical susceptibility window has important implications for determining who is most at risk for chronic respiratory sequelae like asthma. However, identifying the age of RSV infection is impractical in large populations, as not all infections are symptomatic, and measurement thus requires time- and cost-intensive surveillance

SUBMITTER: McKennan CG 

PROVIDER: S-EPMC11998792 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature