The impact of intermittent hypoxemia on type 1 retinopathy of prematurity in preterm infants.

ABSTRACT:

Background

Intermittent hypoxemia (IH) may influence retinopathy of prematurity (ROP) development in preterm infants, however, previous studies had mixed results. This study tests the hypothesis that increased IH is associated with Type 1 ROP; a stage beyond which treatment is indicated.

Methods

IH was quantified by continuously monitoring oxygen saturation (SpO₂) using high-resolution pulse oximeters during the first 10 weeks of life. Statistical analyses assessed the relationship and predictive ability of weekly and cumulative IH for Type 1 ROP development.

Results

Most analyses showed no association between IH and Type 1 ROP adjusting for gestational age (GA) and birth weight (BW). However, cumulative IH of longer duration during weeks 5-10, 6-10, and 7-

SUBMITTER: Rabienia Haratbar S 

PROVIDER: S-EPMC11998977 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature