Repression of ctrA and chpT by a transcriptional regulator of the Xre family that is expressed by RpoN3 and its cognate activator protein in Cereibacter sphaeroides.

ABSTRACT: Cereibacter sphaeroides is an α-proteobacteria that has two flagellar systems. Fla1 directs the assembly of a single subpolar flagellum, and Fla2 directs the assembly of multiple polar flagella. The fla2 genes are controlled by the two-component system CckA/ChpT/CtrA. In the wild-type strain, the fla2 genes are not expressed under the growth conditions commonly used in the laboratory, and thus far, their expression has only been reported in strains carrying either a gain-of-function version of CckA or a null mutation in osp, a negative regulator of CckA. In this work, the differential swimming response of two Fla2 + strains in response to the inclusion of a divalent ion in the culture medium was investigated. This analysis led to identifying a new transcriptional regulator of the XRE famil

SUBMITTER: Vega-Baray B 

PROVIDER: S-EPMC11999139 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature