Dynamics of serum testosterone and biological aging in men: insights from Chinese, American, and British populations.

ABSTRACT:

Background

Biological age (BA) is considered a better predictor of aging than chronological age (CA). BA acceleration was defined as the disparity between BA and CA. However, there has been inconclusive evidence on whether BA acceleration might be reversed by increased total testosterone (TT). The goal of this cross-sectional study was to investigate the relationship between TT and BA acceleration.

Methods

Klemera and Doubal method biological age (KDM-BA) was employed as an indicator of BA in this study. This study involved participants of three ancestries from five cohorts, including the National Health and Nutrition Examination Survey (NHANES, recruited between 1 January 2011 and 31 December 2016), West China Health and Aging Trend (WCHAT, recruited between 1 January 2018

SUBMITTER: Huang W 

PROVIDER: S-EPMC11999286 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature