Case Report: Successful treatment of severe Guillain-Barre syndrome with paralytic ileus as a presenting symptom by intensive immunotherapy.

ABSTRACT: Involvement of the intestinal autonomic nerves in Guillain-Barré syndrome (GBS) can lead to paralytic ileus, a condition commonly observed in severe cases during later stages of the disease. Cases with paralytic ileus as a presenting symptom are very rare. We report a case of a 35-year-old male patient who was admitted to the hospital with acute abdominal pain persisting for 12 hours. Abdominal CT suggested small bowel obstruction, for which routine conventional pharmacological treatment were ineffective. Subsequently, the patient presented with multiple sets of cranial nerve paralysis, bilateral symmetrical delayed paralysis, distal limb numbness, respiratory failure, urinary retention, shock, and electrophysiology, suggesting axonal-type multifocal peripheral nerve damage. Notably, blood

SUBMITTER: Luo L 

PROVIDER: S-EPMC12000006 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature